Article

Progressive developmental cues from multiple cardiac cell types promote cardiomyocyte maturation

2024-06-11

Abstract excerpt

<title>Abstract</title> <p>Accumulating evidence in vitro indicates that the exposure of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) to adult post-natal environmental conditions is not sufficient to attain maturation. Here we instead mimic the progressive embryonic ventricular environment via co-culture of hiPSC-CM with epicardial cells and epicardial-derived cells in two-dimensional (2D...

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Literature Corpus work: 505604e7-62a6-52eb-961c-b8425d4c7f53
DOI: 10.21203/rs.3.rs-4450763/v1

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