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Engineered Microenvironments for Maturation of Stem Cell Derived Cardiac Myocytes

20 Nov 2017

Abstract excerpt

Through the use of stem cell-derived cardiac myocytes, tissue-engineered human myocardial constructs are poised for modeling normal and diseased physiology of the heart, as well as discovery of novel drugs and therapeutic targets in a human relevant manner. This review highlights the recent bioengineering efforts to recapitulate microenvironmental cues to further the maturation state of newly differentiated...

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PMID: 29290797
DOI: 10.7150/thno.19441

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