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Article

Cardiomyocyte Maturation-the Road is not Obstructed.

Stem cell reviews and reports - 1 Dec 2022

Wang Yaning, Yu Miao, Hao Kaili, Lei Wei, Tang Mingliang, Hu Shijun

Abstract excerpt

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) represent one of the most promising ways to treat cardiovascular diseases. High-purity cardiomyocytes (CM) from different cell sources could be obtained at present. However, the immature nature of these cardiomyocytes hinders its further clinical application. From immature to mature state, it involves structural, functional, and metabolic changes in...

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PMID: 35788883
DOI: 10.1007/s12015-022-10407-y

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