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Article

Cathelicidin-deficient mice exhibit increased survival and upregulation of key inflammatory response genes following cecal ligation and puncture.

Journal of molecular medicine (Berlin, Germany) - 1 Sept 2017

Severino Patricia, Ariga Suely Kubo, Barbeiro Hermes Vieira, de Lima Thais Martins, de Paula Silva Elisangela, Barbeiro Denise Frediani, Machado Marcel Cerqueira César, Nizet Victor, Pinheiro da Silva Fabiano

Abstract excerpt

Antimicrobial peptides possess a myriad of molecular properties including bacterial killing and the regulation of many aspects of innate immunity. Cathelicidins are a group of antimicrobial peptides widely investigated by the scientific community. Many studies have focused on the bactericidal and pro-inflammatory roles of cathelicidins. Because the role of endogenous cathelicidin expression remains obscure in...

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PMID: 28623379
DOI: 10.1007/s00109-017-1555-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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