Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macrophage Galactose-Type Lectin-1 Deficiency Is Associated with Increased Neutrophilia and Hyperinflammation in Gram-Negative Pneumonia.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2016

Jondle Christopher N, Sharma Atul, Simonson Tanner J, Larson Benjamin, Mishra Bibhuti B, Sharma Jyotika

Abstract excerpt

C-type lectin receptors (CLRs), the carbohydrate-recognizing molecules, orchestrate host immune response in homeostasis and in inflammation. In the present study we examined the function of macrophage galactose-type lectin-1 (MGL1), a mammalian CLR, in pneumonic sepsis, a deadly immune disorder frequently associated with a nonresolving hyperinflammation. In a murine model of pneumonic sepsis using pulmonary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adoptive Transfer
Share to Extracellular Traps

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gram-Negative Bacterial Infections

Share to Klebsiella pneumoniae

Share to Lectins, C-Type

Share to Leukocytosis

Share to Neutrophil Infiltration

Share to Pneumonia, Bacterial

Source

Open in PubMed Open full text

Identifiers

PMID: 26912318
DOI: 10.4049/jimmunol.1501790
PMCID: PMC4936400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macrophage Galactose-Type Lectin-1 Deficiency Is Associated with Increased Neutrophilia and Hyperinflammation in Gram-Negative Pneumonia.PMID 26912318Read ↗

Proton-Activated Chloride Channel 1 (PACC1) is essential for innate host defense against bacterial sepsisSemantic proximity Read ↗

Dectin-1-Independent Macrophage Phagocytosis of Mycobacterium abscessusSemantic proximity Read ↗

Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils.Semantic proximity Read ↗

<i>Lactobacillus rhamnosus</i> (LR) ameliorates acute respiratory distress syndrome (ARDS) via modulating the lung “Innate Lymphoid Cells (ILCs)-Mononuclear Phagocytic System (MPS)”Semantic proximity Read ↗

Generation of mice deficient for macrophage galactose- and N-acetylgalactosamine-specific lectin: limited role in lymphoid and erythroid homeostasis and evidence for multiple lectins.Semantic proximity Read ↗

Lipoglycans contribute to innate immune detection of mycobacteria.Semantic proximity Read ↗

Lectinophagocytosis of type 1 fimbriated (mannose-specific) Escherichia coli in the mouse peritoneum.Semantic proximity Read ↗

Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor.Semantic proximity Read ↗

Myeloid arginase-1 controls excessive inflammation and modulates T cell responses in Pseudomonas aeruginosa pneumonia.Semantic proximity Read ↗

Mannosyl-recognizing receptors induce an M1-like phenotype in macrophages of susceptible mice but an M2-like phenotype in mice resistant to a fungal infection.Semantic proximity Read ↗

Interleukin-1 promotes coagulation, which is necessary for protective immunity in the lung against Streptococcus pneumoniae infection.Semantic proximity Read ↗

Role of Toll-like receptor 2 in innate resistance to Group B Streptococcus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.