Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced Susceptibility of ADAP-Deficient Mice to Listeria monocytogenes Infection Is Associated With an Altered Phagocyte Phenotype and Function.

Frontiers in immunology - 1 Jan 2021

Böning Martha A L, Parzmair Gerald P, Jeron Andreas, Düsedau Henning P, Kershaw Olivia, Xu Baolin, Relja Borna, Schlüter Dirk, Dunay Ildiko Rita, Reinhold Annegret, Schraven Burkhart, Bruder Dunja

Abstract excerpt

The adhesion and degranulation-promoting adaptor protein (ADAP) serves as a multifunctional scaffold and is involved in the formation of immune signaling complexes. To date, only limited data exist regarding the role of ADAP in pathogen-specific immunity during in vivo infection, and its contribution in phagocyte-mediated antibacterial immunity remains elusive. Here, we show that mice lacking ADAP (ADAPko) are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Disease Susceptibility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity

Share to Listeria monocytogenes

Share to Listeriosis

Share to Phagocytes

Share to Spleen

Source

Open in PubMed Open full text

Identifiers

PMID: 34659211
DOI: 10.3389/fimmu.2021.724855
PMCID: PMC8515145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced Susceptibility of ADAP-Deficient Mice to Listeria monocytogenes Infection Is Associated With an Altered Phagocyte Phenotype and Function.PMID 34659211Read ↗

Paradoxical Roles of the MAL/Tirap Adaptor in PathologiesSemantic proximity Read ↗

Listeria monocytogenes as a probe of immune function.Semantic proximity Read ↗

Cutting edge: protective cell-mediated immunity to Listeria monocytogenes in the absence of myeloid differentiation factor 88.Semantic proximity Read ↗

COMMD10-Guided Phagolysosomal Maturation Promotes Clearance of Staphylococcus aureus in MacrophagesSemantic proximity Read ↗

Mal, more than a bridge to MyD88Semantic proximity Read ↗

RNAseq profiling of leukocyte populations in zebrafish larvae reveals a <i>cxcl11</i> chemokine gene as a marker of macrophage polarization during mycobacterial infectionSemantic proximity Read ↗

Signaling via the MyD88 Adaptor Protein in B Cells Suppresses Protective Immunity during Salmonella typhimurium InfectionSemantic proximity Read ↗

Comparative transcriptomics reveals CrebA as a novel regulator of infection tolerance in D. melanogasterSemantic proximity Read ↗

Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system.Semantic proximity Read ↗

Macrophage LC3-associated phagocytosis is an immune defense against Streptococcus pneumoniae that diminishes with host agingSemantic proximity Read ↗

Cutting edge: myeloid differentiation factor 88 is essential for pulmonary host defense against Pseudomonas aeruginosa but not Staphylococcus aureus.Semantic proximity Read ↗

The inflammasome adaptor pycard is essential for immunity against Mycobacterium marinum infection in adult zebrafishSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.