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Article

The role of mannose receptor during experimental leishmaniasis

29 Jan 2007

Abstract excerpt

The primary host cells for Leishmania replication are macrophages (MP). Several molecules on the surface of professional phagocytic cells have been implicated in the initial process of parasite internalization and initiation of signaling pathways. These pattern recognition receptors distinguish molecular patterns on pathogen surfaces. Mannose receptor (MR), specifically, recognizes mannose residues on the surface...

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Identifiers

PMID: 17261547
DOI: 10.1189/jlb.0706439

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