Article

Differential requirement of Formyl Peptide Receptor 1 in macrophages and neutrophils in the host defense against Mycobacterium tuberculosis Infection.

2024-05-29

Abstract excerpt

<title>Abstract</title> <p>Formyl peptide receptors (FPR), part of the G-protein coupled receptor superfamily, are pivotal in directing phagocyte migration towards chemotactic signals from bacteria and host tissues. Although their roles in acute bacterial infections are well-documented, their involvement in immunity against tuberculosis (TB) remains unexplored. This study investigates the functions of Fpr1 and Fp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e492912d-a1ee-5a9c-83cb-ab54f0c586fc
DOI: 10.21203/rs.3.rs-4421561/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Differential requirement of Formyl Peptide Receptor 1 in macrophages and neutrophils in the host defense against Mycobacterium tuberculosis Infection.DOI 10.21203/rs.3.rs-4421561/v1Read

Interaction of Pattern Recognition Receptors with Mycobacterium TuberculosisSemantic proximity Read

Neutrophil subsets play dual roles in tuberculosis by producing inflammasome dependent-IL-1β or suppressing T-cells via PD-L1Semantic proximity Read

Formyl-peptide receptor 2 governs leukocyte influx in local Staphylococcus aureus infections.Semantic proximity Read

Comparative analysis of Formyl peptide receptor 1 and Formyl peptide receptor 2 reveals shared and preserved signaling profilesSemantic proximity Read

Neutrophil subsets play dual roles in tuberculosis by producing inflammasome dependent-IL-1β or suppressing T-cells via PD-L1Semantic proximity Read

A novel role for C-C motif chemokine receptor 2 during infection with hypervirulent Mycobacterium tuberculosis.Semantic proximity Read

Eosinophils are an integral component of the pulmonary granulocyte response in <i>Tuberculosis</i> and promote host resistance in miceSemantic proximity Read

Genetic Ablation of the Fpr1 Gene Confers Protection from Smoking-Induced Lung Emphysema in MiceSemantic proximity Read

Formyl Peptide Receptor Polymorphisms: 27 Most Possible Ways for Phagocyte Dysfunction.Semantic proximity Read

Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949Semantic proximity Read

Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor.Semantic proximity Read

Paeonol Inhibits the Development of Rheumatoid Arthritis Through the Formyl Peptide Receptor 2Semantic proximity Read