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Article

Cleft lip and palate: understanding genetic and environmental influences.

Nature reviews. Genetics - 1 Mar 2011

Dixon Michael J, Marazita Mary L, Beaty Terri H, Murray Jeffrey C

Abstract excerpt

Clefts of the lip and/or palate (CLP) are common birth defects of complex aetiology. CLP can occur in isolation or as part of a broad range of chromosomal, Mendelian or teratogenic syndromes. Although there has been marked progress in identifying genetic and environmental triggers for syndromic CLP, the aetiology of the more common non-syndromic (isolated) forms remains poorly characterized. Recently, using a...

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Identifiers

PMID: 21331089
DOI: 10.1038/nrg2933
PMCID: PMC3086810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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