Functional evidence of novel tumor suppressor genes for cutaneous malignant melanoma.

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Article

Functional evidence of novel tumor suppressor genes for cutaneous malignant melanoma.

Cancer research - 1 Feb 1999

Parris C N, Harris J D, Griffin D K, Cuthbert A P, Silver A J, Newbold R F

Abstract excerpt

Losses of heterozygosity involving chromosomes 9 and 10 are frequent events in the development and progression of cutaneous malignant melanoma. To investigate whether specifically deleted chromosomal regions encode tumor suppressor genes (TSGs), we introduced normal chromosome 10 into the tumorig...

Topics

Agar
Animals
Carrier Proteins
Cell Cycle Proteins
Cell Division
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 10
Chromosomes, Human, Pair 9
Cloning, Molecular
Cyclin-Dependent Kinase Inhibitor p15

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Cyclin-Dependent Kinase Inhibitor p16

Female

Genes, Tumor Suppressor

Genes, p16

Humans

Melanoma

Mice

Source

Open in PubMed

Identifiers

PMID: 9973191

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9973191-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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