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Article

Evidence for three tumor suppressor loci on chromosome 9p involved in melanoma development.

Cancer research - 1 Feb 2001

Pollock P M, Welch J, Hayward N K

Abstract excerpt

Cytogenetic and loss of heterozygosity (LOH) studies have long indicated the presence of a tumor suppressor gene (TSG) on 9p involved in the development of melanoma. Although LOH at 9p has been reported in approximately 60% of melanoma tumors, only 5-10% of these tumors have been shown to carry CDKN2A mutations, raising the possibility that another TSG involved in melanoma maps to chromosome 9p. To investigate...

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Share to Chromosomes, Human, Pair 9
Share to Genes, p16
Share to Genes, Tumor Suppressor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Homozygote

Share to Loss of Heterozygosity

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Share to Polymorphism, Single-Stranded Conformational

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Identifiers

PMID: 11221846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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