Article
GAS-1: a mitochondrial protein controls sensitivity to volatile anesthetics in the nematode Caenorhabditis elegans.
Anesthesiology - 1 Feb 1999
Kayser E B, Morgan P G, Sedensky M M
Abstract excerpt
BACKGROUND: Mutations in several genes of Caenorhabditis elegans confer altered sensitivities to volatile anesthetics. A mutation in one gene, gas-1(fc21), causes animals to be immobilized at lower concentrations of all volatile anesthetics than in the wild-type, and it does not depend on mutatio...
Topics
- Amino Acid Sequence
- Anesthetics
- Animals
- Caenorhabditis elegans
- Cloning, Molecular
- DNA, Mitochondrial
- Electron Transport Complex I
- Mitochondria
- Molecular Sequence Data
- Mutation
- NADH, NADPH Oxidoreductases
- Quinone Reductases