Mutations conferring new patterns of sensitivity to volatile anesthetics in Caenorhabditis elegans.

doi:10.1097/00000542-199410000-00016

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Article

Mutations conferring new patterns of sensitivity to volatile anesthetics in Caenorhabditis elegans.

Anesthesiology - 1 Oct 1994

Morgan P G, Sedensky M M

Abstract excerpt

BACKGROUND: We previously described the use of the nematode Caenorabditis elegans as a genetic model for studying the mechanism of action of volatile anesthetics. All previous strains of C. elegans with altered responses to anesthetics have been identified by screening the response to halothane....

Topics

Anesthetics
Animals
Caenorhabditis elegans
Chromosome Mapping
Dose-Response Relationship, Drug
Drug Hypersensitivity
Enflurane
Ether
Halothane
Isoflurane
Models, Genetic
Mutation

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