Article
A putative cation channel and its novel regulator: cross-species conservation of effects on general anesthesia.
Current biology : CB - 3 Apr 2007
Humphrey John A, Hamming Kevin S, Thacker Colin M, Scott Robert L, Sedensky Margaret M, Snutch Terrance P, Morgan Phil G, Nash Howard A
Abstract excerpt
Volatile anesthetics like halothane and enflurane are of interest to clinicians and neuroscientists because of their ability to preferentially disrupt higher functions that make up the conscious state. All volatiles were once thought to act identically; if so, they should be affected equally by genetic variants. However, mutations in two distinct genes, one in Caenorhabditis and one in Drosophila, have been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.