Article
Alternatives to mammalian pain models 1: use of C. elegans for the study of volatile anesthetics.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Steele Louise M, Sedensky Margaret M, Morgan Phil G
Abstract excerpt
Performing genetic studies in model organisms is a powerful approach for investigating the mechanisms of volatile anesthetic action. Striking similarities between the results observed in Caenorhabditis elegans and in other organisms suggest that many of the conclusions can be generalized across disparate phyla, and that findings in these model organisms will be applicable in humans. In this chapter, we provide...
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