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Article

TNFalpha*2 marks high risk of severe disease during Plasmodium falciparum malaria and other infections in Sri Lankans.

Clinical and experimental immunology - 1 Feb 1999

Wattavidanage J, Carter R, Perera K L, Munasingha A, Bandara S, McGuinness D, Wickramasinghe A R, Alles H K, Mendis K N, Premawansa S

Abstract excerpt

We have investigated the association between alleles of the genes for tumour necrosis factor-alpha (TNF-alpha) and TNF-beta and severity of disease during malarial (Plasmodium falciparum) and other infections in the Sri Lankan population. Patients were categorized as having either (i) uncomplicated malaria, (ii) severe and complicated malaria, or (iii) severe and complicated infection in which a diagnosis of...

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PMID: 9933464
DOI: 10.1046/j.1365-2249.1999.00804.x
PMCID: PMC1905163

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TNF

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