Article
TNFalpha*2 marks high risk of severe disease during Plasmodium falciparum malaria and other infections in Sri Lankans.
Clinical and experimental immunology - 1 Feb 1999
Wattavidanage J, Carter R, Perera K L, Munasingha A, Bandara S, McGuinness D, Wickramasinghe A R, Alles H K, Mendis K N, Premawansa S
Abstract excerpt
We have investigated the association between alleles of the genes for tumour necrosis factor-alpha (TNF-alpha) and TNF-beta and severity of disease during malarial (Plasmodium falciparum) and other infections in the Sri Lankan population. Patients were categorized as having either (i) uncomplicat...
Topics
- Alleles
- Causality
- Gene Frequency
- Genotype
- Heterozygote
- Humans
- Lymphotoxin-alpha
- Malaria, Falciparum
- Polymorphism, Genetic
- Risk Factors
- Sri Lanka
- Tumor Necrosis Factor-alpha