Article
MAD 20 alleles of merozoite surface protein-1 (msp-1) are associated with severe Plasmodium falciparum malaria in Pakistan.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Apr 2015
Ghanchi Najia Karim, Hasan Zahra, Islam Muniba, Beg Mohammad Asim
Abstract excerpt
BACKGROUND: Various factors determine the outcome of Plasmodium falciparum infection such as parasite load, sequestration, adhesion molecules, and immune mediators. P. falciparum merozoite surface protein-1 (msp-1) and msp-2 genotypes were also found associated with severe disease. We investigated the association between msp-1 and msp-2 genotypes in patients with uncomplicated malaria (UM) and severe malaria...
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