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Article

Activation of gp130 signaling in vivo by the IL-6 super-agonist K-7/D-6 accelerates repopulation of lymphoid organs after irradiation.

European journal of immunology - 1 Jan 1999

Frasca D, Doria G, Barattini P, Guidi F, Salvati A L, Toniatti C, Ciliberto G

Abstract excerpt

Stimulation of the gp130 signaling pathway by IL-6 is known to contribute significantly to hematopoietic expansion in vitro, mostly in combination with other cytokines. In the present study we have investigated whether a similar effect can be observed also in vivo using short-term assays in which irradiated mice were analyzed for repopulation of lymphoid organs. Mice were injected with a combination of soluble...

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Identifiers

PMID: 9933112
DOI: 10.1002/(SICI)1521-4141(199901)29:01<300::AID-IMMU300>3.0.CO;2-J

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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