Article
Interleukin 6 and its receptor in the immune response and hematopoiesis.
International journal of cell cloning - 1 Jan 1990
Hirano T, Taga T, Matsuda T, Hibi M, Suematsu S, Tang B, Murakami M, Kishimoto T
Abstract excerpt
Interleukin 6 (IL-6) plays critical roles in the immune response and hematopoiesis. It is a potent B cell differentiation factor inducing antibody-forming plasma cells. It enhances interleukin 3-induced proliferation of hematopoietic stem cells. Furthermore, IL-6 induces maturation of megakaryocy...
Topics
- Animals
- Antibodies, Monoclonal
- Cell Transformation, Neoplastic
- Cloning, Molecular
- DNA
- Gene Expression
- Hematopoiesis
- Humans
- Immune System
- Interleukin-6
- Mice
- Mice, Transgenic
- Mutation
- Receptors, Immunologic
- Receptors, Interleukin-6
- Signal Transduction
