Isolation of hMRE11B: failure to complement yeast mre11 defects due to species-specific protein interactions.

doi:10.1016/s0378-1119(98)00530-7

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Article

Isolation of hMRE11B: failure to complement yeast mre11 defects due to species-specific protein interactions.

Gene - 28 Dec 1998

Chamankhah M, Wei Y F, Xiao W

Abstract excerpt

The Saccharomyces cerevisiae MRE11 gene plays an important role in meiotic recombination, mitotic DNA repair and telomere maintenance. We present the isolation of hMRE11B cDNA from a human HeLa cell cDNA library as an MRE11 homolog. Compared to the previously identified hMRE11, hMRE11B contains a...

Topics

Base Sequence
Binding Sites
Blotting, Northern
Cloning, Molecular
DNA, Complementary
DNA-Binding Proteins
Dimerization
Endodeoxyribonucleases
Exodeoxyribonucleases
Fungal Proteins
Gene Expression
Genetic Complementation Test

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HL-60 Cells

HeLa Cells

Humans

K562 Cells

MRE11 Homologue Protein

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 9931460
DOI: 10.1016/s0378-1119(98)00530-7

Genes

MRE11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9931460-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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