Article
Isolation of hMRE11B: failure to complement yeast mre11 defects due to species-specific protein interactions.
Gene - 28 Dec 1998
Chamankhah M, Wei Y F, Xiao W
Abstract excerpt
The Saccharomyces cerevisiae MRE11 gene plays an important role in meiotic recombination, mitotic DNA repair and telomere maintenance. We present the isolation of hMRE11B cDNA from a human HeLa cell cDNA library as an MRE11 homolog. Compared to the previously identified hMRE11, hMRE11B contains an additional 84bp sequence that results in a 28 amino-acid insertion close to the C-terminus. The expression pattern of...
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