Article
Renal mechanoreceptor dysfunction: an intermediate phenotype in spontaneously hypertensive rats.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 1999
DiBona G F, Jones S Y, Kopp U C
Abstract excerpt
This study tested the hypothesis that decreased responsiveness of renal mechanosensitive neurons constitutes an intermediate phenotype in spontaneously hypertensive rats (SHR). Decreased responsiveness of these sensory neurons would contribute to increased renal sympathetic nerve activity and sod...
Topics
- Aging
- Animals
- Blood Pressure
- Crosses, Genetic
- Female
- Hypertension
- Kidney
- Male
- Mechanoreceptors
- Phenotype
- Rats
- Rats, Inbred SHR
- Rats, Inbred WKY
