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Article

Renal mechanoreceptor dysfunction: an intermediate phenotype in spontaneously hypertensive rats.

Hypertension (Dallas, Tex. : 1979) - 1 Jan 1999

DiBona G F, Jones S Y, Kopp U C

Abstract excerpt

This study tested the hypothesis that decreased responsiveness of renal mechanosensitive neurons constitutes an intermediate phenotype in spontaneously hypertensive rats (SHR). Decreased responsiveness of these sensory neurons would contribute to increased renal sympathetic nerve activity and sodium retention, characteristic findings in hypertension. A backcross population, developed by mating borderline...

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PMID: 9931150
DOI: 10.1161/01.hyp.33.1.472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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