Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered NGF regulation may link a genetic predisposition for hypertension with hyperactive voiding.

The Journal of urology - 1 Apr 1999

Clemow D B, Spitsbergen J M, McCarty R, Steers W D, Tuttle J B

Abstract excerpt

PURPOSE: Hyperactive voiding and elevated smooth muscle NGF output are traits of the spontaneously hypertensive rat (SHR). Elevated target-derived NGF is associated with hypertension and hyperactive voiding in SHRs. In the present study, we tested for possible genetic links between hypertension, hyperactive voiding and augmented bladder smooth muscle cell (BSMC) NGF secretion. MATERIALS AND METHODS: We crossed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure
Share to Hypertension
Share to Muscle, Smooth

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nerve Growth Factors

Share to Rats, Inbred SHR

Share to Rats, Inbred WKY

Share to Urinary Bladder

Source

Identifiers

PMID: 10081910

Genes

NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Altered NGF regulation may link a genetic predisposition for hypertension with hyperactive voiding.PMID 10081910Read ↗

Effects of growth rate and cell density on nerve growth factor secretion in cultures of vascular and bladder smooth muscle cells from hypertensive and hyperactive rats.Semantic proximity Read ↗

Nerve growth factor gene locus explains elevated renal nerve growth factor mRNA in young spontaneously hypertensive rats.Semantic proximity Read ↗

Nerve growth factor gene and hypertension in spontaneously hypertensive rats.Semantic proximity Read ↗

Aging Changes in Bladder Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels Are Associated With Increasing Heterogeneity of Adrenergic/Mucosal Influence on Detrusor Control in the Mouse.Semantic proximity Read ↗

Renal mechanoreceptor dysfunction: an intermediate phenotype in spontaneously hypertensive rats.Semantic proximity Read ↗

Low affinity nerve growth factor receptor gene co-segregates with decreased bodyweight and increased left ventricular weight in spontaneously hypertensive rats.Semantic proximity Read ↗

Dysfunctional bladder neurophysiology in urofacial syndrome Hpse2 mutant mice.Semantic proximity Read ↗

Mechanisms of increased NGF production in vascular smooth muscle of the spontaneously hypertensive rat.Semantic proximity Read ↗

Increased renal vascular sensitivity to angiotensin II in hypertension is due to decreased response to prostaglandins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.