Exaggerated natriuresis as a candidate intermediate phenotype in spontaneously hypertensive rats.

doi:10.1097/00004872-199816010-00013

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Article

Exaggerated natriuresis as a candidate intermediate phenotype in spontaneously hypertensive rats.

Journal of hypertension - 1 Jan 1998

DiBona G F, Jones S Y, Sawin L L

Abstract excerpt

OBJECTIVE: To determine whether exaggerated natriuresis and exaggerated renal sympathoinhibition during volume loading constitute an intermediate phenotype in spontaneously hypertensive rats. DESIGN: The borderline hypertensive rat, the F1 of a cross between a spontaneously hypertensive rat and a...

Topics

Animals
Blood Pressure
Crosses, Genetic
Female
Heart Rate
Hypertension
Kidney
Male
Natriuresis
Phenotype
Quantitative Trait, Heritable
Rats
Rats, Inbred SHR
Rats, Inbred WKY
Sodium, Dietary
Sympathetic Nervous System

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