Article
Exaggerated natriuresis as a candidate intermediate phenotype in spontaneously hypertensive rats.
Journal of hypertension - 1 Jan 1998
DiBona G F, Jones S Y, Sawin L L
Abstract excerpt
OBJECTIVE: To determine whether exaggerated natriuresis and exaggerated renal sympathoinhibition during volume loading constitute an intermediate phenotype in spontaneously hypertensive rats. DESIGN: The borderline hypertensive rat, the F1 of a cross between a spontaneously hypertensive rat and a normotensive Wistar-Kyoto rat, is a NaCl-sensitive model of genetic hypertension. In addition to hypertension,...
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