Article
Preliminary evidence of linkage of salt sensitivity in black Americans at the beta 2-adrenergic receptor locus.
Hypertension (Dallas, Tex. : 1979) - 1 Apr 1997
Svetkey L P, Chen Y T, McKeown S P, Preis L, Wilson A F
Abstract excerpt
Salt sensitivity is a heritable trait that is a hallmark of hypertension in black Americans. Genes encoding adrenergic receptors are candidate loci for the inheritance of this hypertension-related trait because of the role of these receptors in the regulation of renal sodium excretion and vascular tone. We performed this study to determine whether these loci are responsible for some of the phenotypic variation in...
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