Article
Neuronal responsiveness to central Na+ in 2 congenic strains of Dahl salt-sensitive rats.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 2007
Huang Bing S, Ahmad Monir, Deng Alan Y, Leenen Frans H H
Abstract excerpt
Dahl salt-sensitive rats show increased Na(+) entry into the brain on high salt intake and increased sympathetic and pressor responses to central Na(+). We examined C10QTL2 and C17QTL to test whether they contribute to these phenotypes. In Dahl salt-sensitive, Lewis, and C10S.L16, and C17S.L2 congenic rats on a high salt diet for 8 to 10 days, blood pressure and heart rate were higher in Dahl salt-sensitive...
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