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Article

The stretch-activation response may be critical to the proper functioning of the mammalian heart.

Proceedings of the National Academy of Sciences of the United States of America - 2 Feb 1999

Vemuri R, Lankford E B, Poetter K, Hassanzadeh S, Takeda K, Yu Z X, Ferrans V J, Epstein N D

Abstract excerpt

The "stretch-activation" response is essential to the generation of the oscillatory power required for the beating of insect wings. It has been conjectured but not previously shown that a stretch-activation response contributes to the performance of a beating heart. Here, we generated transgenic mice that express a human mutant myosin essential light chain derived from a family with an inherited cardiac...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9927691
DOI: 10.1073/pnas.96.3.1048
PMCID: PMC15348

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Source receipt: pubmed, retrieved 7 Sept 2026.

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