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Article

Essential light chain S195 phosphorylation is required for cardiac adaptation under physical stress.

Cardiovascular research - 1 Jul 2016

Scheid Lisa-Mareike, Mosqueira Matias, Hein Selina, Kossack Mandy, Juergensen Lonny, Mueller Marion, Meder Benjamin, Fink Rainer H A, Katus Hugo A, Hassel David

Abstract excerpt

AIMS: Regulatory proteins of the sarcomere are pivotal for normal heart function and when affected by mutations are frequently causing cardiomyopathy. The exact function of these regulatory proteins and how mutations in these translate into distinct cardiomyopathy phenotypes remains poorly understood. Mutations in the essential myosin light chain (ELC) are linked to human cardiomyopathy characterized by a marked...

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Identifiers

PMID: 27013636
DOI: 10.1093/cvr/cvw066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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