Telomeric chromatin modulates replication timing near chromosome ends.

doi:10.1101/gad.13.2.146

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Article

Telomeric chromatin modulates replication timing near chromosome ends.

Genes & development - 15 Jan 1999

Stevenson J B, Gottschling D E

Abstract excerpt

Saccharomyces cerevisiae telomeric DNA replicates late in S phase, and telomeric genes are transcriptionally silent. Transcriptional repression of telomere-proximal genes results from silent chromatin initiating at the chromosome end, but the relationship between telomeric chromatin and DNA repli...

Topics

Chromatin
DNA Replication
Fungal Proteins
Mutation
Replication Origin
Repressor Proteins
S Phase
Saccharomyces cerevisiae
Silent Information Regulator Proteins, Saccharomyces cerevisiae
Telomere
Time Factors
Trans-Activators
Transcription, Genetic

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