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Article

Telomeric chromatin modulates replication timing near chromosome ends.

Genes & development - 15 Jan 1999

Stevenson J B, Gottschling D E

Abstract excerpt

Saccharomyces cerevisiae telomeric DNA replicates late in S phase, and telomeric genes are transcriptionally silent. Transcriptional repression of telomere-proximal genes results from silent chromatin initiating at the chromosome end, but the relationship between telomeric chromatin and DNA replication is unknown. Mutations in SIR3, a silent chromatin component, cause telomeric DNA on chromosome V to replicate...

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Identifiers

PMID: 9925638
DOI: 10.1101/gad.13.2.146
PMCID: PMC316395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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