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Article

Analysis of the p21 gene in gliomas.

Journal of neuro-oncology - 1 Nov 1998

Li Y J, Hoang-Xuan K, Zhou X P, Sanson M, Mokhtari K, Faillot T, Cornu P, Poisson M, Thomas G, Hamelin R

Abstract excerpt

The p21 gene encodes a cyclin dependent kinase inhibitor protein (p21) which has a tumor suppressive activity in a variety of tumor cell lines. Since, the p21 gene is up-regulated by the p53 tumor suppressor gene, which is frequently mutated in gliomas, acting therefore in the same control pathwa...

Topics

Alleles
Brain Neoplasms
DNA, Neoplasm
Genes, p53
Glioma
Humans
Mutation
Oncogene Protein p21(ras)

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9892092
DOI: 10.1023/a:1006149021810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9892092-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Analysis of the p21 gene in gliomas.PMID 9892092Read ↗

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