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Analysis of CDKN1A polymorphisms: markers of cancer susceptibility?

Cancer genetics and cytogenetics - 15 Apr 2003

Rodrigues Flávia C C, Kawasaki-Oyama Rosa S, Fo José F Gois, Ukuyama Erica E, Antonio João Roberto, Bozola Antonio R, Romeiro Janaina G, Rahal Paula, Tajara Eloiza H

Abstract excerpt

The CDKN1A (TP21) gene encodes a 21-kD protein that is a critical downstream mediator of wild-type TP53 and an important regulator of the cell cycle. Failure in the function of this gene would be expected to result in abnormal cell proliferation and transformation. Tumor-associated mutations of the coding region of the TP21 are rare. On the other hand, some TP21 polymorphisms have been identified and...

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PMID: 12699883
DOI: 10.1016/s0165-4608(02)00839-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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