Article
Genetic variation in P450c11AS in Chilean patients with low renin hypertension.
The Journal of clinical endocrinology and metabolism - 1 Dec 1996
Fardella C E, Rodriguez H, Montero J, Zhang G, Vignolo P, Rojas A, Villarroel L, Miller W L
Abstract excerpt
Low renin hypertension (LRH), which accounts for 10-20% of patients with idiopathic "essential" hypertension, bears hormonal similarities to mineralocorticoid-induced hypertension, but elevated mineralocorticoid concentrations have not been found. Some patients with LRH have normal, rather than suppressed, plasma aldosterone concentrations, so that the ratio of aldosterone concentration to PRA (Aldo/PRA) is high,...
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