Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic screening for glucocorticoid-remediable aldosteronism (GRA): experience of three clinical centres in Poland.

Journal of applied genetics - 1 Jan 2005

Adler Grazyna, Widecka Krystyna, Peczkowska Mariola, Dobrucki Tomasz, Placha Grzegorz, Drozd Radosław, Parczewski Miłosz, Januszewicz Andrzej, Gaciong Zbigniew, Ciechanowicz Andrzej

Abstract excerpt

Glucocorticoid-remediable aldosteronism (GRA), also known as familial hyperaldosteronism type I (FH-I, OMIM 103900), is a monogenic form of inherited hypertension caused by the presence of a chimaeric gene originating from an unequal cross-over between the CYP11B1 (11beta-hydroxylase) and CYP11B2 (aldosterone synthase) genes. The hybrid gene has the CYP11B1 sequence at the 5' end, including the promoter, and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to 5' Untranslated Regions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chimera

Share to Crossing Over, Genetic

Share to Cytochrome P-450 CYP11B2

Share to Hyperaldosteronism

Share to Poland

Share to Steroid 11-beta-Hydroxylase

Source

Identifiers

PMID: 16110193

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic screening for glucocorticoid-remediable aldosteronism (GRA): experience of three clinical centres in Poland.PMID 16110193Read ↗

[Remediable glucocorticoid hyperaldosteronism: molecular diagnosis].Semantic proximity Read ↗

Glucocorticoid-remediable aldosteronism.Semantic proximity Read ↗

Glucocorticoid remediable aldosteronism: low morbidity and mortality in a four-generation italian pedigree.Semantic proximity Read ↗

Coexistence of different phenotypes in a family with glucocorticoid-remediable aldosteronism.Semantic proximity Read ↗

SFE/SFHTA/AFCE consensus on primary aldosteronism, part 5: Genetic diagnosis of primary aldosteronism.Semantic proximity Read ↗

Glucocorticoid-remediable aldosteronism.Semantic proximity Read ↗

Clinical and gene mutation studies on a Chinese pedigree with glucocorticoid-remediable aldosteronism.Semantic proximity Read ↗

Glucocorticoid-remediable aldosteronism (GRA): diagnosis, variability of phenotype and regulation of potassium homeostasis.Semantic proximity Read ↗

The molecular basis of glucocorticoid-remediable aldosteronism, a Mendelian cause of human hypertension.Semantic proximity Read ↗

Variation of phenotype in patients with glucocorticoid remediable aldosteronism.Semantic proximity Read ↗

A chimaeric llβ-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertensionSemantic proximity Read ↗

Clinical, biochemical and genetic features of five extended kindred's with glucocorticoid-suppressible hyperaldosteronism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.