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Article

Genetic analysis of aldosterone synthase in patients with idiopathic hyperaldosteronism.

The Journal of clinical endocrinology and metabolism - 1 May 1999

Takeda Y, Furukawa K, Inaba S, Miyamori I, Mabuchi H

Abstract excerpt

Idiopathic hyperaldosteronism (IHA) is characterized by hypertension with excessive production of aldosterone, potassium loss, and suppression of the renin-angiotensin system. We compared activity of aldosterone synthase and expression of CYP11B2 messenger RNA (mRNA) in mononuclear leukocytes (MNL) from patients with IHA to findings in leukocytes from patients with aldosterone-producing adenoma and normal...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10323392
DOI: 10.1210/jcem.84.5.5671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic analysis of aldosterone synthase in patients with idiopathic hyperaldosteronism.PMID 10323392Read ↗

Idiopathic hyperaldosteronism: analysis of aldosterone synthase gene.Semantic proximity Read ↗

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Deletion Hybrid Genes, due to Unequal Crossing Over betweenCYP11B1(11β-Hydroxylase) andCYP11B2(Aldosterone Synthase) Cause Steroid 11β-Hydroxylase Deficiency and Congenital Adrenal Hyperplasia1Semantic proximity Read ↗

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