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Article

The production of two Th2 cytokines, interleukin-4 and interleukin-10, is controlled independently by locus Cypr1 and by loci Cypr2 and Cypr3, respectively.

Immunogenetics - 1 Feb 1999

Kosarová M, Havelková H, Krulová M, Demant P, Lipoldová M

Abstract excerpt

The strains BALB/cHeA (BALB/c) and STS/A (STS) differ in production of IL-4 and IL-10, two Th2 cytokines, after stimulation of spleen cells with Concanavalin A, STS being a low and BALB/c a high producer. We analyzed the genetic basis of this strain difference using the recombinant congenic (RC)...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Female
Gene Expression Regulation
Genetic Linkage
Genetic Markers
Genotype
Interleukin-10
Interleukin-4
Male
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Congenic

Mice, Inbred BALB C

Th2 Cells

Source

Identifiers

PMID: 9887350
DOI: 10.1007/s002510050472

Genes

STS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9887350-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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