Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recombinant congenic strains of mice: a new tool for the genetic dissection of efficacy and toxicity of adjuvants.

Vaccine - 14 Feb 2003

Di Marco Sergio, Moisan Jacques, Boghdady Marie-Linda, Skamene Emil, Radzioch Danuta

Abstract excerpt

The efficacy of immunization of a vaccine depends on an antigen, an adjuvant, and on the expression of multiple genes in the host. The responsiveness of various strains of mice to adjuvants is therefore dependent on their genetic background present as a complex, multigenic trait similarly as in man. We have recently developed a gene-discovery platform, termed recombinant congenic strains (RCS), that greatly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adjuvants, Immunologic
Share to Drug Resistance

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Membrane Glycoproteins

Share to Mice, Congenic

Share to Mice, Inbred A

Share to Receptors, Cell Surface

Share to Receptors, Immunologic

Share to Toll-Like Receptors

Source

Identifiers

PMID: 12547590
DOI: 10.1016/s0264-410x(02)00528-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recombinant congenic strains of mice: a new tool for the genetic dissection of efficacy and toxicity of adjuvants.PMID 12547590Read ↗

Recombinant congenic strains derived from A/J and C57BL/6J: a tool for genetic dissection of complex traits.Semantic proximity Read ↗

The AcB/BcA recombinant congenic strains of mice: strategies for phenotype dissection, mapping and cloning of quantitative trait genes.Semantic proximity Read ↗

Susceptibility to tuberculosis as a complex genetic trait: analysis using recombinant congenic strains of mice.Semantic proximity Read ↗

Congenic mice: cutting tools for complex immune disorders.Semantic proximity Read ↗

Mouse genetic model for clinical and immunological heterogeneity of leishmaniasis.Semantic proximity Read ↗

The genetic background influences the cellular and humoral immune responses to vaccines.Semantic proximity Read ↗

Genetic control of Bordetella pertussis infection: identification of susceptibility loci using recombinant congenic strains of mice.Semantic proximity Read ↗

Recombinant congenic strains of mice from B10.D2 and DBA/2: their contribution to behavior genetic research and application to audiogenic seizures.Semantic proximity Read ↗

[Applications of congenic strains in the mouse].Semantic proximity Read ↗

Genotypic and phenotypic characterization of six new recombinant congenic strains derived from NOD/Shi and CBA/J genomes.Semantic proximity Read ↗

Mapping cis-acting regulatory variation in recombinant congenic strains.Semantic proximity Read ↗

Systemic lupus erythematosus--recent clues from congenic strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.