Article
Genetics of susceptibility to radiation-induced lymphomas, leukemias and lung tumors studied in recombinant congenic strains.
International journal of cancer - 26 Nov 1999
Szymanska H, Sitarz M, Krysiak E, Piskorowska J, Czarnomska A, Skurzak H, Hart A A, de Jong D, Demant P
Abstract excerpt
The genetic control of susceptibility to radiation-induced tumors in mice has been tested using the series of 20 CcS/Dem (CcS) Recombinant Congenic Strains, each carrying a different random set of 12.5% of genes of the resistant strain STS/A (STS) on the genetic background of the susceptible strain BALB/cHeA (BALB/c). Two classes of tumors were frequently observed: tumors of the haematopoietic system (lymphomas,...
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