V(H) gene analysis of Burkitt's lymphoma in children from north-western Iran.

doi:10.1046/j.1365-2141.1998.01125.x

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Article

V(H) gene analysis of Burkitt's lymphoma in children from north-western Iran.

British journal of haematology - 1 Dec 1998

Chapman C J, Wright D, Feizi H P, Davis Z, Stevenson F K

Abstract excerpt

Cases of Burkitt's lymphoma (BL) from north-western Iran were investigated for the usage and somatic mutational pattern of their immunoglobulin variable region genes. Potentially functional V(H) genes were amplified from 6/12 of the tumour masses and all of these were derived from the V(H)3 famil...

Topics

Amino Acid Sequence
Amino Acid Substitution
B-Lymphocytes
Burkitt Lymphoma
Child
DNA Mutational Analysis
Female
Humans
Immunoglobulin Variable Region
In Situ Hybridization
Iran
Male
Mutation

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