Article
V(H) gene analysis of Burkitt's lymphoma in children from north-western Iran.
British journal of haematology - 1 Dec 1998
Chapman C J, Wright D, Feizi H P, Davis Z, Stevenson F K
Abstract excerpt
Cases of Burkitt's lymphoma (BL) from north-western Iran were investigated for the usage and somatic mutational pattern of their immunoglobulin variable region genes. Potentially functional V(H) genes were amplified from 6/12 of the tumour masses and all of these were derived from the V(H)3 family, with 4/6 being derived from the most commonly used V(H)3 family member, V3-23. All of the tumour sequences were...
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