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Article

The genetic variability of the VH genes in follicular lymphoma: the impact of the hypermutation mechanism.

British journal of haematology - 1 Dec 1999

Noppe S M, Heirman C, Bakkus M H, Brissinck J, Schots R, Thielemans K

Abstract excerpt

Follicular lymphoma (FL) cells have inherited an activated hypermutation mechanism from their origin of germinal centre B cells. Based on today's knowledge of the intrinsic properties related to this mechanism and the VH base composition, reconsideration of previous reports should be made on a broader range of samples. The present study examined the mutation pattern of the VH genes expressed by 55 cases of FL. FL...

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Source

Identifiers

PMID: 10583269
DOI: 10.1046/j.1365-2141.1999.01732.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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