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Article

Immunoglobulin heavy chain variable region gene usage and mutational status of the leukemic B cells in Iranian patients with chronic lymphocytic leukemia.

Cancer science - 1 Dec 2009

Hojjat-Farsangi Mohammad, Jeddi-Tehrani Mahmood, Razavi Seyed Mohsen, Sharifian Ramazan Ali, Mellstedt Hakan, Shokri Fazel, Rabbani Hodjatallah

Abstract excerpt

The mutational status of the immunoglobulin variable region heavy chain genes (IGHV) is an important prognostic marker in chronic lymphocytic leukemia (CLL). The data accumulated in the literature has largely been derived from studies conducted on Caucasian Western populations. Little is known about Asian CLL patients. In this study the IGHV genes usage and somatic hypermutation status have been investigated in...

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Identifiers

PMID: 19824994
DOI: 10.1111/j.1349-7006.2009.01341.x
PMCID: PMC11158136

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Source receipt: pubmed, retrieved 7 Sept 2026.

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