Pharmacogenetic Effects of Naltrexone in Individuals of East Asian Descent: Human Laboratory Findings from a Randomized Trial.

doi:10.1111/acer.13586

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Article

Pharmacogenetic Effects of Naltrexone in Individuals of East Asian Descent: Human Laboratory Findings from a Randomized Trial.

Alcoholism, clinical and experimental research - 1 Mar 2018

Ray Lara A, Green ReJoyce, Roche Daniel J O, Bujarski Spencer, Hartwell Emily E, Lim Aaron C, Rohrbaugh Taylor, Ghahremani Dara, Hutchison Kent, Miotto Karen

Abstract excerpt

BACKGROUND: Genetic variation in the endogenous opioid system has been identified as 1 potential source of individual variability in naltrexone treatment outcomes. The majority of naltrexone pharmacogenetic studies have focused on a particular single nucleotide polymorphism (SNP) of the mu-opioid receptor gene (OPRM1; rs1799971; commonly known as the Asn40Asp SNP) in Caucasian samples with decidedly mixed...

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Identifiers

PMID: 29265379
DOI: 10.1111/acer.13586
PMCID: PMC6086578

Genes

OPRM1

Variants

rs1799971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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