Article
Association of protein-tyrosine phosphatase PTP-BAS with the transcription-factor-inhibitory protein IkappaBalpha through interaction between the PDZ1 domain and ankyrin repeats.
The Biochemical journal - 15 Jan 1999
Maekawa K, Imagawa N, Naito A, Harada S, Yoshie O, Takagi S
Abstract excerpt
PTP-BAS is a membrane-associated protein tyrosine phosphatase containing a band-4.1 homology region and five PDZ (PSD-95 Dlg ZO-1) [discs-large homology region ('DHR')/Gly-Leu-Gly-Phe ('GLGF')] domains. The second and fourth PDZ domains were reported to associate with Fas/CD95. By using the first...
Topics
- Ankyrins
- Binding Sites
- DNA-Binding Proteins
- HeLa Cells
- Humans
- I-kappa B Proteins
- Mutation
- NF-KappaB Inhibitor alpha
- Nerve Tissue Proteins
- Peptide Fragments
- Phosphorylation
- Protein Binding
- Protein Tyrosine Phosphatase, Non-Receptor Type 13
- Protein Tyrosine Phosphatases