Article
The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling.
Current biology : CB - 11 Oct 2005
Anjum Rana, Roux Philippe P, Ballif Bryan A, Gygi Steven P, Blenis John
Abstract excerpt
The viability of vertebrate cells depends on a complex signaling interplay between survival factors and cell-death effectors. Subtle changes in the equilibrium between these regulators can result in abnormal cell proliferation or cell death, leading to various pathological manifestations. Death-associated protein kinase (DAPK) is a multidomain calcium/calmodulin (CaM)-dependent Ser/Thr protein kinase with an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
