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Effect of plating medium and phage storage on mutant frequency and titer in the lambda cII transgenic mutation assay.

Environmental and molecular mutagenesis - 1 Jan 1998

Zimmer D M, Harbach P R, Mattes W B, Aaron C S

Abstract excerpt

We examined several experimental parameters of the lambda cI/cII transgenic mutation assay. In the assay, clear plaque lambda phage mutants are identified in a positive selection scheme following rescue of the lambda/LIZ shuttle vector from frozen tissues of Big Blue" transgenic mice. Mutant frequency and titer of phage from various tissues of control and ENU-treated animals was essentially the same on LB or TB1...

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PMID: 9882006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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