Article
A novel Escherichia coli-derived mutation detected with the Big Blue cII mutant selectable assay.
Environmental and molecular mutagenesis - 1 May 2010
Ward Tonya L, Prtenjaca Anita, Hill Kathleen A
Abstract excerpt
Transgenic mouse mutation detection systems allow investigation of the origins and mechanisms of mutation associated with exogenous and endogenous mutagen exposures in individual tissues and cell types. In the past, selection assays for transgenic mutants have been contaminated with nonmurine-derived mutations and assay validation is critical to ensure murine in vivo origins of mutations. This is critical in...
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