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Article

Ten allelic apolipoprotein[a] 5' flanking fragments exhibit comparable promoter activities in HepG2 cells.

Journal of lipid research - 1 Aug 1995

Bopp S, Köchl S, Acquati F, Magnaghi P, Pethö-Schramm A, Kraft H G, Utermann G, Müller H J, Taramelli R

Abstract excerpt

Plasma levels of the atherogenic lipoprotein[a] represent a quantitative genetic trait that is primarily controlled by the polymorphic apolipoprotein[a] locus on chromosome 6q. The more than 1000-fold variation in lipoprotein[a] plasma levels is explained to a large extent by a remarkable size polymorphism of the apolipoprotein[a] gene which is translated into apolipoprotein[a] isoforms and by unidentified...

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Source

Identifiers

PMID: 7595093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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Ten allelic apolipoprotein[a] 5' flanking fragments exhibit comparable promoter activities in HepG2 cells.PMID 7595093Read ↗

Studies of apolipoprotein (a) promoter from subjects with different plasma lipoprotein (a) concentrations.Semantic proximity Read ↗

Identification of promoter sequences in the 5' untranslated region of the baboon apolipoprotein[a] gene.Semantic proximity Read ↗

Transcription efficiency of human apolipoprotein A-I promoter varies with naturally occurring A to G transition.Semantic proximity Read ↗

Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene.Semantic proximity Read ↗

Plasma lipoprotein(a) levels and expression of the apolipoprotein(a) gene are dependent on the nucleotide polymorphisms in its 5'-flanking region.Semantic proximity Read ↗

Transcriptional regulatory mechanisms of the human apolipoprotein genes in vitro and in vivo.Semantic proximity Read ↗

Sequence polymorphisms in the apo(a) gene associated with specific levels of Lp(a) in plasma.Semantic proximity Read ↗

Sequence and functional changes in a putative enhancer region upstream of the apolipoprotein(a) gene.Semantic proximity Read ↗

Functional analysis of human promoter polymorphisms.Semantic proximity Read ↗

Polymorphism in the human apolipoprotein A-I gene promoter region. Association of the minor allele with decreased production rate in vivo and promoter activity in vitro.Semantic proximity Read ↗

A common Hpa I RFLP of apolipoprotein C-I increases gene transcription and exhibits an ethnically distinct pattern of linkage disequilibrium with the alleles of apolipoprotein E.Semantic proximity Read ↗

Transcriptional regulation of the human apolipoprotein genesSemantic proximity Read ↗

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