Article
Oestradiol decreases rat apolipoprotein AI transcription via promoter site B.
Journal of molecular endocrinology - 1 Oct 2000
Taylor A H, Fox-Robichaud A E, Egan C, Dionne J, Lawless D E, Raymond J, Romney J, Wong N C
Abstract excerpt
Oestrogens protect against ischaemic heart disease in the post-menopausal female by increasing serum concentrations of apolipoprotein (apo) AI and the abundance of high-density lipoprotein particles. In men and experimental male animals, the administration of oestrogen has variable effects on apo AI expression. As the major mode of oestrogen action on target genes involves regulating promoter activity and hence...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
