Polymorphism in the promoter region of the apolipoprotein AI gene associated with differences in apolipoprotein AI levels: the European Atherosclerosis Research Study.

doi:10.1002/gepi.1370110305

Back to search

Article

Polymorphism in the promoter region of the apolipoprotein AI gene associated with differences in apolipoprotein AI levels: the European Atherosclerosis Research Study.

Genetic epidemiology - 1 Jan 1994

Talmud P J, Ye S, Humphries S E

Abstract excerpt

The effect associated with the substitution of adenine (A) for guanidine (G) in the promoter region of the apolipoprotein AI gene (-75 bp) with plasma apo AI and high-density lipoprotein (HDL) levels was investigated in the European Atherosclerosis Research Study (EARS). This is a study of health...

Topics

Adenine
Adolescent
Adult
Age Factors
Alleles
Apolipoprotein A-I
Base Sequence
Case-Control Studies
DNA
Europe
Fathers
Female
Gene Frequency
Genetic Variation
Guanidine
Guanidines
Homozygote
Humans

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.