Guanidine to adenine (G/A) substitution in the promoter region of the apolipoprotein AI gene is associated with elevated serum apolipoprotein AI levels in Chinese non-smokers.

doi:10.1002/gepi.1370110304

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Article

Guanidine to adenine (G/A) substitution in the promoter region of the apolipoprotein AI gene is associated with elevated serum apolipoprotein AI levels in Chinese non-smokers.

Genetic epidemiology - 1 Jan 1994

Saha N, Tay J S, Low P S, Humphries S E

Abstract excerpt

The influence of the guanidine to adenine (G/A) substitution in the promoter region of the apolipoprotein (apo) AI gene (at -75 bp) on serum lipids and apolipoproteins was studied in 287 healthy Chinese of both sexes in Singapore. Women had significantly higher levels of high-density lipoprotein cholesterol (HDLC) and apo AI and lower low-density lipoprotein cholesterol (LDLC). The distribution of genotypes was...

Topics

Adenine
Adult
Alleles
Apolipoprotein A-I
Base Sequence
China
Cholesterol, HDL
Cholesterol, LDL
Confidence Intervals
DNA
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Frequency

Genotype

Guanidine

Guanidines

Humans

Male

Middle Aged

Source

Open in PubMed

Identifiers

PMID: 8088506
DOI: 10.1002/gepi.1370110304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8088506-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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