Article
E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains.
Oncogene - 1 Jul 2004
Logan Nicola, Delavaine Laurent, Graham Anne, Reilly Carmel, Wilson Jon, Brummelkamp Thijn R, Hijmans E Marielle, Bernards René, La Thangue Nicholas B
Abstract excerpt
The E2F family of transcription factors play an important role in regulating cell cycle progression. We report here the characterization and functional properties of a new member of the human E2F family, referred to as E2F-7. E2F-7 has two separate DNA-binding domains, a feature that distinguishes E2F-7 from other mammalian E2F proteins, but resembling the organization of recently isolated E2F-like proteins from...
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