Article
Dephosphorylation of barrier-to-autointegration factor by protein phosphatase 4 and its role in cell mitosis.
The Journal of biological chemistry - 10 Jan 2014
Zhuang Xiaolei, Semenova Elena, Maric Dragan, Craigie Robert
Abstract excerpt
Barrier-to-autointegration factor (BAF or BANF1) is highly conserved in multicellular eukaryotes and was first identified for its role in retroviral DNA integration. Homozygous BAF mutants are lethal and depletion of BAF results in defects in chromatin segregation during mitosis and subsequent nuclear envelope assembly. BAF exists both in phosphorylated and unphosphorylated forms with phosphorylation sites Thr-2,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
